Punteggi predittivi per aiutare nella scelta terapeutica: lo score PRECISE DAPT Un aspetto da tempo dibattuto in cardiologia è costituito dalla durata della doppia aggregazione antipiastrinica (DAPT), ovvero l’aggiunta all’acido acetilsalicilico di una...

Importance  Heart disease (HD) and cancer are the 2 leading causes of death in the United States. During the first decade of the 21st century, HD mortality declined at a much greater rate than cancer mortality and it appeared that cancer would overtake HD as the...

Objective To study the effectiveness and safety of the non-vitamin K antagonist oral anticoagulants (novel oral anticoagulants, NOACs) dabigatran, rivaroxaban, and apixaban compared with warfarin in anticoagulant naïve patients with atrial fibrillation....

In 2013, the European Heart Rhythm Association (EHRA) published a Practical Guide on the use of non-VKA oral anticoagulants (NOACs) in patients with atrial fibrillation (AF) (Heidbuchel H, Verhamme P, Alings M, Antz M, Hacke W, Oldgren J, Sinnaeve P, Camm AJ,...

Background  Patients with diabetes appear to be at elevated risk of atherothrombotic events. Objectives  The purpose of this study was to determine the effect of antiplatelet therapy with ticagrelor on recurrent ischemic events in patients with diabetes and prior...

Direct oral anticoagulants (DOACs) have been used in clinical practice in the United States for the last 4 to 6 years. Although DOACs may be an attractive alternative to warfarin in many patients, long-term outcomes of use of these medications are unknown. We...

Abstract Background  Risk stratification in asymptomatic patients remains by far the most important yet unresolved clinical problem in the Brugada syndrome (BrS). Objectives  This study sought to analyze the usefulness of electrocardiographic parameters as markers...

Most physician readers of Aro’s and Chugh’s elegant review of electrical and anatomic types of LVH and the implications will be puzzled by the concepts that electrical LVH (ECG/LVH) and anatomic LVH (echo/LVH and MRI/LVH) might be different entities, and that...

Dopo l’endorsement dei giorni scorsi ricevuto dello staff interno dell’Fda, lo scorso 15 gennaio il nuovo antiaggregante orale vorapaxar ha ricevuto il parere positivo  degli esperti del Cardiovascular and Renal Drugs Advisory Committee dell’Fda. Con 10 voti a 1,...

Objectives  The aim of this study was to describe current practice regarding completeness of revascularization in patients with multivessel disease undergoing percutaneous coronary intervention (PCI) and to investigate the association of incomplete...

Allopurinol lowers blood pressure in adolescents and has other vasoprotective effects. Whether similar benefits occur in older individuals remains unclear. We hypothesized that allopurinol is associated with improved cardiovascular outcomes in older adults with...

Background  Diagnosed diabetes mellitus (DM) is a consistently documented risk factor for ischemic stroke in patients with atrial fibrillation (AF). Objectives  The purpose of this study was to assess the association between duration of diabetes and elevated...

This investigation sought to quantify the risk factors for short-term readmission in patients with heart failure (HF). Electronic databases were systematically searched for studies reporting relative risk, odds ratio, and hazard ratio for the combined primary...

Adiponectin is a key component in multiple metabolic pathways. Studies evaluating associations of adiponectin with clinical outcomes in older adults have reported conflicting results. We investigated the association of adiponectin with mortality and cardiovascular...